For cancer cells to metastasize, they must first break free of a tumor's own defenses. Most tumors are sheathed in a protective "basement" membrane—a thin, pliable film that holds cancer cells in place as they grow and ...
Mar 8, 2021
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(Medical Xpress)—The blood-brain barrier (BBB) prevents most large or hydrophilic (polar) molecules from getting into the brain. For many neurological diseases, like Parkinson's, the presence of the BBB severely limits ...
Metastases are largely responsible for the death rate of patients with solid cancers; the prognosis of cancer patients reduces significantly if metastases are diagnosed. Until now there has been no procedure available to ...
Mar 4, 2024
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The majority of breast cancers start in the lining of a breast milk duct and, if they remain there, are very treatable. But once these cancers become invasive—breaking through a thin matrix around the duct, called the basement ...
Nov 14, 2023
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Researchers at Turku University and Åbo Akademi University, Finland, have identified that finger-like cellular extensions called filopodia contribute to building a barrier surrounding breast tumors.
Oct 25, 2022
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Cells in the gut send secret messages to the immune system. Thanks to new research from the La Jolla Institute for Immunology (LJI), scientists finally got a look at what they're saying.
Jul 29, 2022
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A new study adds to the evidence that chemotherapy enhances cancer's spread beyond the primary tumor, showing how one chemo drug allows breast cancer cells to squeeze through and attach to blood vessel linings in the lungs.
Nov 2, 2021
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All cancers are the result of cells that have gone haywire, multiplying out of control and expanding beyond their normal constraints. But not all tumors are the same: for reasons that remain poorly understood, some are more ...
Sep 3, 2020
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Nearly two decades after a class of once-promising cancer drugs called MMP inhibitors mysteriously failed in clinical trials, scientists think they may have an explanation for what went wrong.
Jan 24, 2019
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Cancers pose the greatest danger when they become invasive and then spread from their originating tissues throughout the body.
Oct 9, 2018
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