Alzheimer's disease & dementia

Brain receptor cell could be new target for Alzheimer's

Blocking a key receptor in brain cells that is used by oxygen free radicals could play a major role in neutralizing the biological consequences of Alzheimer's disease, according to researchers at Temple University.

Alzheimer's disease & dementia

Alzheimer's drugs fail, but lessons are learned

Dr. Stephen Salloway pulls no punches in describing the results of two clinical trials of the Alzheimer's drug bapineuzumab that he helped to lead. The antibody failed to produce cognitive improvement for volunteers compared ...

Alzheimer's disease & dementia

Mechanism in Alzheimer's-related memory loss identified

Cleveland Clinic researchers have identified a protein in the brain that plays a critical role in the memory loss seen in Alzheimer's patients, according to a study to be published in the journal Nature Neuroscience and posted ...

Alzheimer's disease & dementia

Enzyme BACE1 may be important in predicting onset of Alzheimer disease

The critical enzyme beta-secretase1 (BACE1) is known to be elevated in brains with sporadic Alzheimer disease (AD). Scientists have now found increased levels of BACE1 in brains with mild cognitive impairment (MCI), suggesting ...

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