Alzheimer's disease & dementia

BACE-Inhibitor successfully tested in Alzheimer's animal model

The protein amyloid beta is believed to be the major cause of Alzheimer's disease. Substances that reduce the production of amyloid beta, such as BACE inhibitors, are therefore promising candidates for new drug treatments. ...

Alzheimer's disease & dementia

Blood test identifies key Alzheimer's marker

A new study led by researchers at Washington University School of Medicine in St. Louis suggests that measures of amyloid beta in the blood have the potential to help identify people with altered levels of amyloid in their ...

Alzheimer's disease & dementia

Structural analysis of relevant drug targets for Alzheimer's disease

Alzheimer's Disease (AD) is classified as a neurodegenerative non-curable disease that affects millions worldwide. Current drugs have side effects that are significant. In AD, the beta-amyloid precursor protein (β-APP) that ...

Alzheimer's disease & dementia

Never before seen images of early stage Alzheimer's disease

Researchers at Lund University in Sweden have used the MAX IV synchrotron in Lund – the strongest of its kind in the world - to produce images that predate the formation of toxic clumps of beta-amyloid, the protein believed ...

Alzheimer's disease & dementia

Gut bacteria may play a role in Alzheimer's disease

New research from Lund University in Sweden has shown that intestinal bacteria can accelerate the development of Alzheimer's disease. According to the researchers behind the study, the results open up the door to new opportunities ...

Alzheimer's disease & dementia

New worm strain to facilitate study of Alzheimer's disease

Researchers from Yale-NUS College have partnered with researchers from the National University of Singapore (NUS) and SingHealth Group to develop a novel Caenorhabditis elegans (C. elegans) worm strain which expresses an ...

Alzheimer's disease & dementia

Trial drug shows 'impressive' Alzheimer's action: study

An experimental drug cleared protein buildup in the brains of people with mild Alzheimer's disease and slowed their mental decline, the results of a preliminary trial showed Wednesday.

page 7 from 10