Many bugs that make us sick—bacteria, viruses, fungi and parasites—hide out in our cells in protective little bubbles called vacuoles. To clear an infection, the immune system must recognize and destroy these vacuoles ...
Sep 28, 2015
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About half of all tumors are missing a gene called p53, which helps healthy cells prevent genetic mutations. Many of these tumors develop resistance to chemotherapy drugs that kill cells by damaging their DNA.
Oct 22, 2015
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Interleukin-10 (IL-10) is an anti-inflammatory cytokine protein that reduces immune responses and staves off autoimmune disease. Now, a research team led by Masato Kubo at the RIKEN Research Center for Allergy and Immunology, ...
Jun 17, 2011
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In a finding that may be good news for scientists developing HIV vaccines and therapies, a team of researchers at The Rockefeller University and the Howard Hughes Medical Institute have found a way to investigate the broadly ...
Jul 20, 2011
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Researchers have traced in detail how certain powerful HIV neutralizing antibodies evolve, a finding that generates vital clues to guide the design of a preventive HIV vaccine, according to a study appearing in Science Express ...
Aug 11, 2011
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Several genes have been linked to ALS, with one of the most recent called FUS. Two new studies in PLoS Biology, one from the University of Pennsylvania School of Medicine, and the other from colleagues at Brandeis University, ...
Apr 26, 2011
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Penn Medicine researchers have discovered that hypermethylation - the epigenetic ability to turn down or turn off a bad gene implicated in 10 to 30 percent of patients with Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal ...
Mar 20, 2015
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In a new study published today in Cell Reports, scientists at the Fred Hutchinson Cancer Research Center demonstrate that mice lacking one copy of a gene called CTCF have abnormal DNA methylation and are markedly predisposed ...
May 2, 2014
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A team led by researchers at Brigham and Women's Hospital and Harvard Medical School has taken a step toward solving a central mystery of Parkinson's disease: What is the normal function of the protein whose misfolding causes ...
Sep 5, 2022
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Chewing, breathing, and other regular bodily functions that we undertake "without thinking" actually do require the involvement of our brain, but the question of how the brain programs such regular functions intrigues scientists.
May 14, 2015
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