G protein-coupled receptors (GPCRs) are the largest family of membrane protein receptors. The proteins control how tissues and organs function. More than one-third of current drugs target these receptors.
Nov 5, 2020
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Chemokine receptors, located at the surface of many immune cells, play an important role in cell function. Chemokines are small proteins that bind to these receptors and control the movement and behavior of white blood cells.
Jun 16, 2021
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People diagnosed with schizophrenia critically rely upon treatment with antipsychotic medications to manage their symptoms and help them function at home and in the workplace.
Sep 3, 2015
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Scientists at the National Institutes of Health have identified new genetic risk factors for two types of non-Alzheimer's dementia. These findings were published in Cell Genomics and detail how researchers identified large-scale ...
May 8, 2023
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New research led by Unity Health Toronto that examines how fibroblast cells in the body are activated to cause fibrosis and organ scarring has been published in Nature Reviews Molecular Cell Biology. Fibrosis and organ scarring ...
May 8, 2024
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Scientists modified a protein in the heart which dramatically reduced cell damage after heart attacks, according to new research published the American Heart Association journal Arteriosclerosis, Thrombosis and Vascular Biology.
Mar 1, 2012
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There's not much difference between what makes a man and what makes his beer - at least at the molecular level - according to a new study led by Professor John Schwabe at the University of Leicester.
Jul 1, 2013
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Many lines of evidence indicate that schizophrenia is a disorder of neurodevelopment. For example, genes implicated in the heritable risk for schizophrenia are also implicated in the development of nerve cells and their connections. ...
Mar 6, 2013
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Walter and Eliza Hall Institute scientists have revealed new details about how cell signalling is controlled in the immune system, identifying in the process potential new therapeutic targets for treating severe blood disorders.
Feb 16, 2012
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UT Southwestern researchers used cryo-electron microscopy (cryo-EM) to determine the near-atomic structure of the smallest membrane protein solved to date. Their work could lead to better immunotherapies in cancer and improved ...
Mar 6, 2019
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