A new therapeutic strategy for hepatocellular cancer (HCC) that initially primes the tumor with an immune checkpoint inhibitor before using a multikinase inhibitor drug showed great promise for treating patients with the ...
Mar 16, 2022
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A new research perspective titled "Targeting GITR in cancer immunotherapy—there is no perfect knowledge" has been published in Oncotarget.
Jun 21, 2023
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Immunotherapy has revolutionized the way we treat cancer in recent years. Instead of targeting the tumor itself, immunotherapies work by directing patients' immune systems to attack their tumors more effectively. This has ...
May 15, 2024
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Just as the body's immune system can fight off infection, it can be a powerful weapon against cancer. Harnessing and fine-tuning that weapon, however, will require a better understanding of the complex interactions between ...
Nov 22, 2023
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A new study from researchers at the UCLA Jonsson Comprehensive Cancer Center helps explain how disruptions in genes can lead to the resistance to one of the leading immunotherapies, PD-1 blockade, and how new drug combinations ...
May 28, 2020
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Locally advanced cervical cancer remains an area of high therapeutic need, with recent trials failing to demonstrate evidence of benefit from adjuvant chemotherapy or immune checkpoint blockade administered concurrent with ...
Mar 27, 2023
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Persistent protein expression may explain why tumors return after therapy in glioblastoma patients, according to a study published on March 5th in the Journal of Experimental Medicine.
Mar 5, 2012
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Cancer experts have tried, sometimes unsuccessfully, to use the total number of mutations in a tumor, called the tumor mutation burden (TMB), to predict a patient's response to immunotherapy. Now, investigators at the Johns ...
Jan 26, 2023
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A vast number of microbes colonizes the human body to form an ecological community known as the microbiota. Microbiota are made up of bacteria, viruses, fungi, and archaea. These microbes are closely associated with the physiology ...
Aug 10, 2023
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Patients receiving neuromuscular blocking medications as part of their anesthetic regimen should be carefully monitored to ensure the best care and outcomes, according to recent—and independently developed—guidelines ...
Jun 5, 2023
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