Genetics

Another byproduct of aging: Hypermutations in the brain

Genetic mutations in early development have been implicated in several psychiatric disorders such as autism and schizophrenia, symptoms of which typically manifest during childhood and early adulthood. However, mutations ...

Medical research

A nuclear gatekeeper that regulates bone formation

Important insights into the cellular processes underlying healthy bone formation and development have been gleaned by a RIKEN-led study into a previously unknown bone disorder1.

Genetics

New taxonomy of non-skeletal rare disorders with impact on bone

Thanks to major progress in the understanding and management of rare congenital diseases and syndromes, many patients with these rare disorders are now living longer lives. With this progress it has become apparent that many ...

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