A rare and as-yet-unnamed skeletal disorder shares a common "signaling pathway" with another rare skeletal disorder called Jansen metaphyseal chondrodysplasia. (A signaling pathway is a group of molecules in a cell that work ...
Oct 9, 2018
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Malaria caused by Plasmodium parasites is a life-threatening infectious disease that kills at least half a million people annually while causing over 200 million new infections. In some cases, complications can quickly develop ...
Jun 2, 2017
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A study published today in the journal Nature Cell Biology shows that chronic exposure to an inflammatory "emergency" signal, interleukin-1, causes blood-forming bone marrow stem cells to produce cells needed to fight infection ...
Apr 25, 2016
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Researchers working with mice believe there's hope for patients with a rare genetic disorder that turns their muscle into bone, in essence immobilizing them in an extra skeleton.
Sep 2, 2015
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Our bones are smart. Bones know that by adolescence it's time to stop growing longer and stronger, and from that point on bones keep their shape by healing injuries.
Nov 24, 2014
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Experiments in mice with a bone disorder similar to that in women after menopause show that a scientifically overlooked group of cells are likely crucial to the process of bone loss caused by the disorder, according to Johns ...
Oct 5, 2014
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An enzyme therapy may prevent skeletal abnormalities associated with the genetic disorder neurofibromatosis type-1, Vanderbilt investigators have discovered.
Aug 14, 2014
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A healthy adult must generate as many as one hundred billion new red blood cells each day, to maintain the numbers circulating in his blood. A team of EPFL researchers has identified a key step in the process by which red ...
Mar 14, 2013
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A paper published online today in Nature describes the results of using bone marrow transplant (BMT) to replace faulty immune system cells in models of Rett Syndrome. The procedure arrested many severe symptoms of the childhood ...
Mar 18, 2012
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Researchers from Nijmegen and Newcastle have discovered a new genetic mutation leading to severe combined immune deficiency disorder (SCID). It's the first time a mutation in the proteasome, a molecular shredder, has been ...
Mar 19, 2024
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