By combining engineered polymeric materials known as hydrogels with complex intestinal tissue known as organoids - made from human pluripotent stem cells - researchers have taken an important step toward creating a new technology ...
Oct 23, 2017
0
1084
Many people associate the word "bacteria" with something dirty and disgusting. Dr. Pere Santamaria disagrees. Called the microbiome, the bacteria in our bodies have all kinds of positive effects on our health, Santamaria ...
Oct 23, 2017
0
15
Using human induced pluripotent stem cells (iPSCs), a Massachusetts General Hospital research team has bioengineered functional small intestine segments that, when implanted into rats, were capable of deliver nutrients into ...
Oct 10, 2017
1
35
Nerve cells in the gut play a crucial role in the body's ability to marshal an immune response to infection, according to a new study from Weill Cornell Medicine scientists.
Sep 7, 2017
0
171
Immune cells patrol the gut to ensure that harmful microbes hidden in the food we eat don't sneak into the body. Cells that are capable of triggering inflammation are balanced by cells that promote tolerance, protecting the ...
Aug 3, 2017
1
830
Genes that regulate a cellular recycling system called autophagy are commonly mutated in Crohn's disease patients, though the link between biological housekeeping and inflammatory bowel disease remained a mystery. Now, researchers ...
Jul 27, 2017
0
95
Using an array of modern biochemical and structural biology techniques, researchers from Boston University School of Medicine (BUSM) have begun to unravel the mystery of how acidity influences a small protein called serum ...
Jul 27, 2017
0
3
Scientists have made an important step in understanding the organisation of nerve cells embedded within the gut that control its function - a discovery that could give insight into the origin of common gastrointestinal diseases, ...
May 19, 2017
4
170
A Massachusetts General Hospital (MGH) research team has found how a variant in an important epigenetic enzyme—previously associated by population-based genetic studies with Crohn's disease and other immune disorders—interferes ...
Mar 3, 2017
0
83
The natural life cycle of cells that line the intestine is critical to preserving stable conditions in the gut, according to new research led by a Weill Cornell Medicine investigator. The findings may lead to the development ...
Mar 1, 2017
0
79
