Oncology & Cancer

Targeting protein could prevent metastasis of cancer cells

(Medical Xpress)—Researchers at King's College London have uncovered a protein required by cancer cells to spread to other parts of the body, highlighting it as a potential target for future treatments to prevent secondary ...

Oncology & Cancer

Discovery reveals important clues to cancer metastasis

In recent years investigators have discovered that breast tumors are influenced by more than just the cancer cells within them. A variety of noncancerous cells, which in many cases constitute the majority of the tumor mass, ...

Oncology & Cancer

Endotrophin links obesity to breast cancer progression

Fat cells (adipocytes) surround breast tumors and contribute to tumor growth by expressing factors that aid oncogenesis. Col6 is a protein that is highly expressed in adipocytes and its expression is further increased in ...

Oncology & Cancer

LIFR protein suppresses breast cancer metastasis

A receptor protein suppresses local invasion and metastasis of breast cancer cells, the most lethal aspect of the disease, according to a research team headed by scientists from The University of Texas MD Anderson Cancer ...

Oncology & Cancer

Modeling metastasis

Cancer metastasis, the escape and spread of primary tumor cells, is a common cause of cancer-related deaths. But metastasis remains poorly understood. Studies indicate that when a primary tumor breaks through a blood vessel ...

Oncology & Cancer

TRPM7 protein key to breast cancer metastasis in animal models

The protein transient receptor potential melastatin-like 7 (TRPM7) is a critical determinant of breast cancer cell metastasis, according to study results published in Cancer Research, a journal of the American Association ...

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