Medical research

Skeletal imitation reveals how bones grow atom-by-atom

Researchers from Chalmers University of Technology, Sweden, have discovered how our bones grow at an atomic level, showing how an unstructured mass orders itself into a perfectly arranged bone structure. The discovery offers ...

Medical research

Mutations, CRISPR, and the biology behind movement disorders

Scientists at the RIKEN Center for Brain Science (CBS) in Japan have discovered how mutations related to a group of movement disorders produce their effects. Published in Proceedings of the National Academy of Sciences, the ...

Medical research

Study opens new therapeutic avenue for mitochondria malfunction

A surprising offender has been emerging to drive the progression of Parkinson's, Alzheimer's, Huntington's and other neurodegenerative diseases: calcium. Calcium controls the production of fuel in mitochondria, the cell's ...

Neuroscience

Surfing on calcium waves: A larva's journey to becoming a fly

Eric Carl, in his much-loved children's book The Very Hungry Caterpillar, documents the transformation of a gluttonous caterpillar into a beautiful butterfly. For a scientist, metamorphosis poses many unaddressed questions. ...

Alzheimer's disease & dementia

New biomarker for Alzheimer's disease found via CRISPR technique

The objective of the research, undertaken in the laboratories of the IBPM, is to develop a model for studying Alzheimer's disease (AD) of sporadic origin—in other words, AD that is not due to a hereditary genetic mutation. ...

Medical research

Sarcolipin tricks muscle cells into using more energy, burning fat

Ever wonder why you burn fat and heat up when you exercise or shiver? Now, researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) have shown that sarcolipin, a small peptide only found in muscles, increases ...

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