The health impacts of a complex protein that plays a major role in the development of Alzheimer's disease and heart conditions can be lessened by three kinds of drug inhibitors, according to scientists at the University of ...
Mar 22, 2024
0
1
Scientists at the University of Colorado Anschutz Medical Campus have made a 'paradigm shifting' discovery on the mechanisms required for learning and memory that could lead to new therapies for Alzheimer's disease and potentially ...
Aug 30, 2023
0
40
Ruxolitinib, a drug that is already approved by the U.S. Food and Drug Administration (FDA) for treating certain cancers and skin conditions, is effective at inhibiting CaMKII, a protein kinase linked to cardiac arrhythmias.
Jun 21, 2023
1
66
A form of gene therapy protects optic nerve cells and preserves vision in mouse models of glaucoma, according to research supported by NIH's National Eye Institute. The findings suggest a way forward for developing neuroprotective ...
Jul 22, 2021
0
196
Neurons are the primary cells of the nervous system, and the signals that are transmitted between them are responsible for all our actions and our cognitive ability. In particular, learning and memory are believed to be associated ...
Feb 9, 2021
0
0
One of the new realities in biomedical research is that it's increasingly difficult to use a general approach to score advances. Now, investigations into disease mechanisms, for example, are often conducted at the molecular ...
Aug 10, 2020
0
81
Forty years since its discovery, much remains to be discovered about an enzyme called CaMKII that plays a key role in shaping learning and memory in the brain.
Feb 21, 2020
0
9
Time can be measured in many ways: a watch, a sundial, or the body's natural circadian rhythms. But what about the sexual behavior of a fruit fly?
Dec 6, 2019
0
815
A new study from researchers at Max Planck Florida Institute for Neuroscience (MPFI) has shed light on the unexpected mechanism that allows calcium/calmodulin-dependent protein kinase, or CaMKII, to decode and translate calcium ...
Jun 27, 2019
0
0
After a 30-year quest, a Brandeis professor has discovered the molecule that stores long-term memories—it's called calcium/calmodulin dependent protein kinase, or CaMKII for short. The results were published on September ...
Sep 28, 2017
0
155
