Oncology & Cancer

Synthetic RNAs designed to fight cancer

(Medical Xpress)—In search of better cancer treatments, researchers at Washington University School of Medicine in St. Louis have designed synthetic molecules that combine the advantages of two experimental RNA therapies.

Oncology & Cancer

Protein folding becomes cancer treatment target

(Medical Xpress)—A molecule that helps cancer cells to keep dividing could be a promising target for new treatments, according to research published in the journal Oncogene.

Oncology & Cancer

Biologists ID new cancer weakness

About half of all cancer patients have a mutation in a gene called p53, which allows tumors to survive and continue growing even after chemotherapy severely damages their DNA.

Genetics

Mutations in cancer often affect the X chromosome

Every case of cancer originates from changes in a person's genetic material (mutations). These usually occur as "somatic mutations" in individual cells during an individual's lifetime, rather than being inherited from a person's ...

Medical research

Protein 'motif' crucial to telomerase activity

It is difficult to underestimate the importance of telomerase, an enzyme that is the hallmark of both aging and the uncontrolled cell division associated with cancer. In an effort to understand and control telomerase activity, ...

Oncology & Cancer

Cancer: Unraveling a mechanism behind cellular proliferation

A hallmark of cancer is uncontrolled and sustained cell division. One particular overactive protein is implicated in this malfunction. EPFL scientists have discovered a complex mechanism that regulates this protein's activity ...

Oncology & Cancer

Researchers identify potential biomarker for cancer diagnosis

Scientists studying cancer development have known about micronuclei for some time. These erratic, small extra nuclei, which contain fragments, or whole chromosomes that were not incorporated into daughter cells after cell ...

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