Rhabdomyosarcoma, a malignant tumor, is one of the most common soft tissue tumors occurring during childhood. The tumors are associated with skeletal muscle and can emerge anywhere in the body. Consequently, the clinical ...
Jul 26, 2023
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Cisplatin is a potent chemotherapeutic agent used to treat various cancers, including cervical cancer. But the continued use of cisplatin can lead to the development of cisplatin resistance and other side effects, like chemotherapy-induced ...
Jul 20, 2023
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Researchers at the UCLA Jonsson Comprehensive Cancer Center have confirmed that a large number of genetic variants of unknown significance are in fact verified mutations that predispose patients to a rare hereditary syndrome ...
Jul 13, 2023
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Cancer cells with extra chromosomes depend on those chromosomes for tumor growth, a new Yale study reveals, and eliminating them prevents the cells from forming tumors. The findings, said the researchers, suggest that selectively ...
Jul 6, 2023
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New research from Sanford Burnham Prebys has helped explain how melanoma evades the immune system and may guide the discovery of future therapies for the disease. The study found that a protein known to be active in immune ...
Jul 5, 2023
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Scientists at St. Jude Children's Research Hospital found immune and tumor cells compete over glutamine, a major nutrient in their local environment, with significant implications for anti-cancer activity. If cancer cells ...
Jul 5, 2023
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Cancer spreads throughout the human body in cunning, almost militaristic, ways. For example, it can manipulate our genetic make-up, take over specific cell-to-cell signaling processes, and mutate key enzymes to promote tumor ...
Jul 3, 2023
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Therapeutic antibodies that cause aggressive tumors to become susceptible to treatment are being studied with the hope of one day changing the fate of patients who either relapse soon after cancer therapy or whose stubborn ...
Mutations in the KRAS gene are the major driver of pancreatic cancer. The resulting protein controls multiple signaling pathways involved in cell growth and survival. In cancer, the gene is mutated to be permanently "on," ...
Jun 29, 2023
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Northwestern Medicine scientists have identified a novel vulnerability in a subset of genes commonly mutated in cancer, according to a study recently published in the Journal of Clinical Investigation.
Jun 26, 2023
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