Inflammatory disorders

From grave to cradle: Collagen-induced gut cell reprogramming

Most cells have a pretty normal life: they're born, they grow, they get old, and they die. But the Benjamin Buttons of the cellular world can go from old to young again in the right context. Now, researchers from Japan have ...

Medical research

The molecules behind metastasis

Many cancer cells never leave their original tumors. Some cancer cells evolve the ability to migrate to other tissues, but once there cannot manage to form new tumors, and so remain dormant. The deadliest cancer cells are ...

Oncology & Cancer

Taming overactive molecular signaling in renal cell cancer

In a new study from the Johns Hopkins Kimmel Cancer Center, researchers described a novel mechanism of tumor formation in kidney cancers driven by overexpression of the mechanistic target of rapamycin complex 1 (mTORC1) signaling ...

Oncology & Cancer

Impact of epigenetics on the clinical management of cancer patients

In the early 1980s, the first changes in DNA related to a chemical modification called methylation were discovered, followed by the discovery in the mid-1990s of the first tumor suppressor genes inactivated by these modifications ...

Oncology & Cancer

Cracking the mystery behind a deadly brain cancer

The brain cancer, glioblastoma, is a fierce and formidable opponent. Its millions of victims include Senator John McCain, President Biden's son, Beau, and famed film critic Gene Siskel, to name just a few. Most patients succumb ...

page 32 from 40