Researchers at Uppsala university have developed a new method to find mutations in brain tumors in children. They also showed that the mutations change how cancer cells respond to a cancer drug. These findings could lead ...
Aug 7, 2023
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In a landmark study of 125 Australian children with high-risk cancer—whose tumor cells were grown in the lab and tested against a suite of potential therapies—Children's Cancer Institute researchers have found that they ...
Aug 2, 2023
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Esophageal adenocarcinoma (EAC) is a highly lethal cancer, with a five-year survival rate of less than 20%. Although a precursor lesion to EAC, called Barrett's esophagus (BE), is present in roughly 7% of middle-aged adults, ...
Jul 27, 2023
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The median length of survival after diagnosis of glioblastoma is 14 months, but some of these brain tumors are more aggressive and resistant to treatment than others, and a new study from Sylvester Comprehensive Cancer Center ...
Jul 3, 2023
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Researchers at The University of Texas MD Anderson Cancer have engineered a new model of aggressive renal cell carcinoma (RCC), highlighting molecular targets and genomic events that trigger chromosomal instability and drive ...
Jun 26, 2023
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In a paper published in NAR Cancer, researchers from the Center for Childhood Cancer Research at Nationwide Children's and their collaborators report a comprehensive 3D chromatin structural analysis and characterization of ...
Jun 14, 2023
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Rates of colorectal cancer are high despite widespread adoption of screening programs in many high-income European countries. Such programs tend to use a one-size-fits-all approach where most people are screened starting ...
Jun 11, 2023
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Identifying people at high risk of chronic disease means that they can be targeted with prevention measures before they become sick. Polygenic risk scores, where genomic information alone is used to assess the risk of developing ...
Jun 9, 2023
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The p53 gene is one of the most important in the human genome: the only role of the p53 protein that this gene encodes is to sense when a tumor is forming and to kill it. While the gene was discovered more than four decades ...
May 4, 2023
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Modern drugs can be very effective at treating cancer and have led to greatly improved survival rates. However, some cancer treatments can cause damage to the heart, or cardiotoxicity. This damage can present in a range of ...
Apr 27, 2023
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