The Warburg Effect describes a phenomenon in which cancer cells voraciously consume glucose for energy—something scientists have long known, yet have had little success exploiting as a way to stunt tumor growth.
Sep 14, 2017
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T lymphocytes found in tumors and implicated in killing tumor cells cope with the shortage of oxygen and nutrients in the tumor microenvironment by using fat as the main source of energy. Promoting a switch from glucose to ...
Sep 11, 2017
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3
Epigenetic changes are chemical modifications that turn our genes off or on. In a new study from Uppsala University, researchers show that tea consumption in women leads to epigenetic changes in genes that are known to interact ...
May 31, 2017
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In humans, developing metabolic disease, particularly type 2 diabetes, is correlated with having bacteria that penetrate the mucus lining of the colon, according to a study led by Drs. Benoit Chassaing and Andrew Gewirtz ...
May 30, 2017
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198
A new study shows cells in the initial stage of cancer change their metabolism before getting eliminated by the surrounding normal cells, providing a novel target for developing cancer prevention drugs.
May 15, 2017
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A diagnosis of pancreatic cancer is a virtual death sentence, with only 3 to 5 per cent of patients surviving beyond five years. A key reason that it has the lowest survival rate of all major cancers is that it readily spreads ...
May 9, 2017
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Scientists at the Luxembourg Institute of Health (LIH) have discovered hitherto unknown molecular mechanism by which the human immune system activates its immune cells. T cells that express a gene known as Gclc effectively ...
Apr 19, 2017
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Liver cancers are a major cause of cancer-related deaths. Large-scale genetic analyses have associated liver cancer with dysregulation of numerous molecular pathways, but disruptions in insulin signaling pathways appear to ...
Apr 10, 2017
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0
When it comes to preventing colorectal cancer, there's a whole lot more to it than colonoscopy.
Mar 24, 2017
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Researchers in China have discovered that a metabolic enzyme called AKR1B1 drives an aggressive type of breast cancer. The study, "AKR1B1 promotes basal-like breast cancer progression by a positive feedback loop that activates ...
Mar 7, 2017
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