Cancerous tumors are classified primarily based on their tissue of origin. However, the sequencing of the human genome and the development of powerful and affordable DNA sequencing technologies has ushered in a new era of ...
Apr 24, 2019
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Many cancer therapies do not produce the hoped-for results. A common reason for this is that the tumors develop resistance to the medications. This is the case, for example, with alpelisib, a drug that has been approved for ...
Apr 11, 2023
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(Medical Xpress)—The gene known to be associated with breast cancer susceptibility, BRCA 1, plays a critical role in the normal metabolic function of skeletal muscle, according to a new study led by University of Maryland ...
Mar 12, 2014
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Researchers at Washington University School of Medicine in St. Louis have identified four important signs and symptoms that signal an elevated risk of early-onset colorectal cancer. These red flags may be key to earlier detection ...
May 4, 2023
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Contrary to what you might think, cancer and diabetes appear to have some biology in common. According to a report in the September 30th issue of the Cell Press journal, Cell, a pathway that initially drew attention for its ...
Sep 29, 2011
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Cancer cells commonly rely on glycolysis, the type of metabolism that does not use oxygen to generate their energy however, researchers from Queen Mary University of London's Barts Cancer Institute and the Spanish National ...
Sep 10, 2015
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Immunologists at St. Jude Children's Research Hospital have discovered that tumors use a unique mechanism to switch on regulatory T cells to protect themselves from attack by the immune system. Surprisingly, the mechanism ...
Feb 24, 2021
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Cancer cells usually live in an environment with limited supplies of the nutrients they need to proliferate — most notably, oxygen and glucose. However, they are still able to divide uncontrollably, producing new cancer ...
Nov 21, 2011
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A biomedical startup that licensed a Purdue University technology has developed a late-stage prostate cancer therapy that could provide an alternative to current hormone therapies that are known to develop resistance after ...
Oct 13, 2016
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Inhibiting telomerase, an enzyme that rescues malignant cells from destruction by extending the protective caps on the ends of chromosomes, kills tumor cells but also triggers resistance pathways that allow cancer to survive ...
Feb 21, 2012
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