Oncology & Cancer

New insights into melanoma development and therapy

Malignant melanoma is a type of skin cancer that originates from melanocytes or nevi, causing about 80% of skin cancer-related deaths. While some cases have shown significant response to existing molecular targeted therapies, ...

Oncology & Cancer

First-in-class targeted microRNA therapy slows cancer tumor growth

A new cancer therapy developed by Purdue University researchers attacks tumors by tricking cancer cells into absorbing a snippet of RNA that naturally blocks cell division. As reported in Oncogene, tumors treated with the ...

Oncology & Cancer

Rethinking and rigor brings promising protein for cancer therapy

The elucidation of the role of a critical protein in cell biology is paving the way for alternative cancer treatments. By refuting recent challenges that threatened to invalidate their work, a team of KAUST researchers investigating ...

Immunology

Researchers identify lipid vascular 'ZIP code'

Researchers at Rutgers Cancer Institute of New Jersey and Rutgers New Jersey Medical School (NJMS), together with other collaborating groups, have discovered the first lipid vascular "ZIP code" in the lungs. Getting a drug ...

Endocrinology & Metabolism

Metabolism meets signaling to fine-tune cell growth

Cells use a variety of metabolic pathways to synthesize the building blocks for growth and proliferation. To ensure balanced growth, these biosynthetic processes must be tightly coordinated. Researchers from the Max Planck ...

Oncology & Cancer

RNA stability may play a role in prostate cancer

Mutations in a genetic region that regulates RNA stability could influence prostate cancer outcomes and drug resistance, according to new work from scientists at Fred Hutchinson Cancer Center published in Cell Reports.

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