One of the major challenges in cancer research and clinical care is understanding the molecular basis for therapeutic resistance as a major cause of long-term treatment failures. In cases of melanoma, the main targeted therapeutic ...
Feb 1, 2024
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The number of new cancer cases will rise to more than 35 million in 2050—77 percent higher than the figure in 2022, the World Health Organization's cancer agency warned Thursday.
Feb 1, 2024
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The neurons that make up our brains and nervous systems mature slowly over many months. And while this may be beneficial from an evolutionary standpoint, the slow pace makes growing cells to study neurodegenerative and neurodevelopmental ...
Jan 31, 2024
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Depending on their location, cancer cells within a three-dimensional (3D) tumor structure can have different microenvironments. Cells in the core of the tumor receive less oxygen (hypoxia) and nutrients than those in the ...
Jan 30, 2024
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Investigators from the UCLA Health Jonsson Comprehensive Cancer Center have identified a protein called UCHL1 in highly aggressive neuroendocrine carcinomas and neuroblastoma that could potentially be used as a molecular ...
Jan 29, 2024
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A protein in the immune system can be manipulated to help overcome bowel cancer, according to new research from The Australian National University (ANU). The research is published in Science Advances.
Jan 26, 2024
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A new study has found that the circadian clock—which synchronizes physiological and cellular activities with the day-night cycle and is generally thought to be tumor suppressive—in fact has a contextually variable role ...
Jan 24, 2024
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Imaging the tumors of patients with advanced melanoma receiving pembrolizumab (Keytruda) after only one week—rather than the standard of around three months—identified metabolic changes that corresponded with treatment ...
Jan 24, 2024
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A new case report titled "Lazarus effect in a patient initially empirically treated with osimertinib for EGFR L858R mutant non-small cell lung cancer with leptomeningeal disease: a case report" has been published in Oncotarget.
Jan 24, 2024
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A new research perspective titled "Bone marrow adipocytes provide early sign for progression from mgus to multiple myeloma" has been published in Oncotarget.
Jan 22, 2024
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