Researchers from Drexel's College of Medicine have identified new drugs that show early success in shrinking breast cancer tumors that have metastasized in the brain. The discovery marks the first time that targeting a key ...
Jul 18, 2024
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A distinct signaling pathway called TNF-α drives the transformation of epithelial cells into aggressive tumor cells. During cancer progression, cells activate their own TNF-α program and become invasive. This finding could ...
Jul 17, 2024
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Sneaking by cancer's defenses, by disguising tumor-fighting antibodies inside the molecules cancer uses to nourish tumor growth, is the basis of a novel therapy from Yale Cancer Center researchers at the Yale School of Medicine ...
Jul 16, 2024
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Investigators at the UCLA Health Jonsson Comprehensive Cancer Center have uncovered new details about the role of a protein called interferon regulatory factor (IRF1) in cancer progression and treatment response, offering ...
Jul 16, 2024
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Splenic venous hypertension (SVH), also known as left-sided portal hypertension, is a rare condition characterized by upper gastrointestinal (GI) bleeding in the absence of liver disease. This condition arises due to increased ...
Jul 16, 2024
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Colorectal cancer is the second leading cause of cancer deaths worldwide and the third most diagnosed cancer, affecting over a million people annually. The problem worsens if the tumor is metastatic, meaning it moves from ...
Jul 15, 2024
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Immunotherapy can be a highly effective treatment for non-small cell lung cancer (NSCLC), but some patients are resistant to the therapy or develop intolerable side effects.
Jul 12, 2024
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A number of cancers, including certain brain and liver tumors, as well as myeloid leukemias, are driven by mutations in the enzyme isocitrate dehydrogenase 1, or IDH1. Drugs that block mutated IDH1 (mIDH1) have recently come ...
Jul 12, 2024
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The primary goal in cancer drug research is not merely to discover compounds that can destroy cancer cells, but to develop methods that specifically target and deliver these agents to cancer cells, sparing healthy ones.
Jul 12, 2024
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Early findings from a small clinical trial provide evidence that a new cellular immunotherapy approach may be effective in treating metastatic solid tumors. In the trial, researchers from the National Institutes of Health ...
Jul 11, 2024
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