Genetics

Getting straight to the heart of the matter in stem cells

The process by which embryonic stem cells develop into heart cells is a complex process involving the precisely timed activation of several molecular pathways and at least 200 genes. Now, Salk Institute scientists have found ...

Cardiology

Beating heart patch is large enough to repair the human heart

Biomedical engineers at Duke University have created a fully functioning artificial human heart muscle large enough to patch over damage typically seen in patients who have suffered a heart attack. The advance takes a major ...

Medical research

Magnetic cellular Legos for the regenerative medicine of the future

By incorporating magnetic nanoparticles in cells and developing a system using miniaturized magnets, researchers at the Laboratoire Matière et Systèmes Complexes (CNRS/Université Paris Diderot) and collaborators have created ...

Cardiology

Id genes play surprise role in cardiac development

Researchers from Sanford Burnham Prebys Medical Discovery Institute (SBP), the Cardiovascular Institute at Stanford University and other institutions were surprised to discover that the four genes in the Id family play a ...

Cardiology

A heart attack in a petri dish

In petri dishes in her campus laboratory at New Jersey Institute of Technology, Alice Lee is developing colonies of cardiac cells, formed into chambers, that pump and contract like a human heart. Derived from stem cells, ...

Medical research

Cardiac stem cells from heart disease patients may be harmful

Patients with severe and end-stage heart failure have few treatment options available to them apart from transplants and "miraculous" stem cell therapy. But a new Tel Aviv University study finds that stem cell therapy may, ...

Medical research

Stem cells show promise – but they also have a darker side

Everyone seems to be excited about stem cells. Their excellent promise as a treatment for a range of diseases and injuries mean almost guaranteed coverage for research. While some types of stem cells are already being used ...

Genetics

Induced pluripotent stem cells don't increase genetic mutations

It's been more than 10 years since Japanese researchers Shinya Yamanaka, M.D., Ph.D., and his graduate student Kazutoshi Takahashi, Ph.D., developed the breakthrough technique to return any adult cell to its earliest stage ...

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