Oncology & Cancer

Feedback loop promotes cancer cells' adaption to molecular stress

Investigators from the laboratory of Marc Mendillo, Ph.D., associate professor of Biochemistry and Molecular Genetics, have discovered new cellular regulators of a cancer cell transcription factor linked to cancer resilience ...

Medical research

White matter may aid recovery from spinal cord injuries: Study

Injuries, infection and inflammatory diseases that damage the spinal cord can lead to intractable pain and disability. Some degree of recovery may be possible. The question is, how best to stimulate the regrowth and healing ...

Genetics

How epigenetics influence memory formation

When we form a new memory, the brain undergoes physical and functional changes known collectively as a "memory trace." A memory trace represents the specific patterns of activity and structural modifications of neurons that ...

Oncology & Cancer

Knockout of CD5 on CAR T cells shown to boost anti-tumor efficacy

The effectiveness of CAR T cell therapy against a variety of cancers, including solid tumors, could be boosted greatly by using CRISPR-Cas9 technology to knock out the gene for CD5, a protein found on the surface of T cells, ...

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