Oncology & Cancer
Form drives function in cancer proliferation
A new study finds that the protein responsible for the crawling movements of cells also drives the ability of cancer cells to grow when under stress.
May 6, 2019
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Page 3 - News tagged with cell cytoskeleton
Medical research
Changing the perspective on the 'Cinderella of the cytoskeleton'
SETD2 is a protein well known as a chromatin remodeler, one that helps turn genes on or off by modifying histone proteins in the nucleus of the cell. When researchers discovered that SETD2 is mutated or lost in several cancer ...
Dec 23, 2020
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Medical research
Genetic disease linked to protein build-up
Mutations of the gene Lmna previously thought to be directly responsible for a group of laminopathies—serious developmental conditions including premature aging and a form of muscular dystrophy—in fact cause them by allowing ...
Aug 29, 2012
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Medical research
Integrins losing their grip drive activate T cell immune responses
When integrins let go of their ligands and the actin cytoskeleton inside the dendritic cell, the activity of another cell surface receptor, the GM-CSF receptor, rises. This increased signaling induces the dendritic cells ...
Oct 29, 2014
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Medical research
Key target responsible for triggering detrimental effects in brain trauma identified
Researchers studying a type of cell found in the trillions in our brain have made an important discovery as to how it responds to brain injury and disease such as stroke. A University of Bristol team has identified proteins ...
Jul 25, 2013
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Diseases, Conditions, Syndromes
Cancer drug can rebalance kidney function in a devastating genetic disease
Researchers at the University of Cambridge and the University of Zurich have discovered that a drug newly approved for cancer improves kidney dysfunction in a mouse model of Dent disease 2 and Lowe syndrome
Sep 9, 2020
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Oncology & Cancer
Spread of cancer cells may be slowed by targeting of protein
(Medical Xpress)—The spread of cancer cells may be slowed by targeting the protein km23-1, according to researchers at Penn State College of Medicine.
Dec 18, 2012
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Medical research
New methods help to improve attachment of an implant to bone
Replacement of prostheses is unpleasant to the patient and expensive to society. Replacement of failed hip prostheses gives rise to an expenditure of about 10 million euros yearly in Finland. A usual reason for the need to ...
Mar 13, 2013
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Neuroscience
Boundary stops molecule right where it needs to be
A molecule responsible for the proper formation of a key portion of the nervous system finds its way to the proper place not because it is actively recruited, but instead because it can't go anywhere else.
May 24, 2012
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Genetics
Study finds some people have a uniquely human gene that enhances immune function
University at Buffalo researchers have found that the active form of a gene promotes a broad range of protective traits. The gene is found in 75% of the population and is known to protect against neurodegeneration. Now, UB ...
Apr 30, 2024
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