Breast cancer that spreads often infiltrates bone, causing fractures and intense pain. In such cases, chemotherapy is ineffective because the environment of the bone protects the tumor, even as the drug has toxic side effects ...
Sep 27, 2017
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Scientists at the Salk Institute for Biological Studies have found clues to the functioning of an important damage response protein in cells. The protein, p53, can cause cells to stop dividing or even to commit suicide when ...
Jun 30, 2011
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When autologous (self-donated) lung-derived mensenchymal stem cells (LMSCs) were transplanted endoscopically into 13 adult female sheep modeled with emphysema, post-transplant evaluation showed evidence of tissue regeneration ...
Jun 4, 2012
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Scientists have identified a key enzyme responsible for destroying lung tissue in tuberculosis (TB), they report today in the Journal of Clinical Investigation. Drugs that inhibit this enzyme are already available, meaning ...
Apr 25, 2011
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Once breast cancer spreads through the body, it can degrade a patient's healthy bones, causing numerous problems. Scientists at Huntsman Cancer Institute (HCI) at the University of Utah have identified a new way that bones ...
Jan 25, 2017
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Osteoarthritis is a leading cause of disability, characterized by the destruction of cartilage tissue in joints, but there is a lack of effective therapies because the underlying molecular causes have been unclear. A study ...
Feb 13, 2014
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University of Texas Medical Branch at Galveston researchers have discovered that the commonly used antidepressant drug paroxetine could also become a therapy for the vascular complications of diabetes.
Dec 14, 2012
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Most degenerative diseases begin with a gradual loss of specific cell types that progresses, eventually leading to symptoms. For example, in type I diabetes, hyperglycemia commonly develops when approximately 80 percent of ...
May 16, 2011
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The toxic byproducts produced by the breakdown of unsaturated fats lead to a higher likelihood of severe inflammation, cell death and multi-system organ failure among acute pancreatitis patients who are obese, say researchers ...
Nov 2, 2011
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One promising area in the fight against cancer is the use of nanotechnology - the manipulation of matter at an atomic and molecular scale for specific medical aims.
Aug 9, 2013
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