A new approach to target an 'undruggable' prostate cancer driver
New research suggests a novel strategy to target a genetic anomaly that occurs in half of all prostate cancers.
Mar 23, 2017
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New research suggests a novel strategy to target a genetic anomaly that occurs in half of all prostate cancers.
Mar 23, 2017
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Geneticists led by University of Utah Nobel Prize Laureate Mario R. Capecchi, Ph.D., have engineered mice that develop clear cell sarcoma (CCS), a significant step in better understanding how this rare and deadly soft tissue ...
Feb 11, 2013
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UCLA researchers have discovered the molecular basis of, and identified potential treatment for, an incurable disease known as inclusion body myopathy, Paget disease with frontotemporal dementia, or IBMPFD. Using both genetically ...
Mar 21, 2017
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Researchers have identified a potential new pathway in prostate cancer cells by which cancer-driving gene products can be generated, according to a study published in Cancer Discovery, a journal of the American Association ...
Jun 19, 2012
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A new research perspective titled "HER3- A key survival pathway and an emerging therapeutic target in metastatic colorectal cancer and pancreatic ductal adenocarcinoma" has been published in Oncotarget.
May 24, 2023
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Leukaemia arises as a result of genetic or epigenetic alterations in blood cells, leading to an aberrant accumulation of undifferentiated blasts. Understanding the molecular pathogenesis and aetiology of infant leukaemia ...
Oct 15, 2012
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A team of scientists has demonstrated the mechanism by which ETO2-GLIS2, a gene fusion, promotes the development of an aggressive form of pediatric leukemia. The findings, published in Cancer Cell, also reveal an opportunity ...
May 9, 2017
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