Researchers at the Washington University School of Medicine, St. Louis, have discovered a potential new target for cancer immunotherapy in transposable elements (TEs), short segments of DNA that can move around the genome.
One of the great challenges in the fight against cancer is to design new technologies for a personalized treatment for each patient. Depending on the molecular characteristics—DNA mutations for instance—of each tumor, ...
Mar 31, 2023
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A research team of 37 scientists, led by the Technical University of Munich, has developed a method to interrogate drug-induced post-translational modifications (PTMs) in a time and dose-dependent way.
A global team of researchers has created an algorithmic tool that can identify existing drugs in order to combat future pandemics. The work, reported in the Cell Press journal Heliyon, offers the possibility of responding ...
Mar 6, 2023
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Cannabidiol or CBD, a non-psychoactive component of cannabis, inhibits the metabolism of nicotine, new research has found, meaning it could help tobacco users curb the urge for that next cigarette.
Feb 16, 2023
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The protein STAT5 has long been an appealing target against cancer, but after decades of research it was consigned to the "undruggable" category. Now, University of Michigan Rogel Cancer Center researchers have found success ...
Feb 15, 2023
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In a new study, researchers found that the PFAS chemical GenX suppresses the neutrophil respiratory burst—the method white blood cells known as neutrophils use to kill invading pathogens. The study is an important first ...
Feb 15, 2023
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Tumor cells typically alter their energy metabolism and increase glucose uptake to support their rapid division and spread. This limits glucose availability for immune cells and therefore dampens the body's anti-cancer immune ...
Feb 14, 2023
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Although hepatitis E is a common disease, little is known about the life cycle of the virus. Initial findings on how it manages to infect cells are reported by a team from Molecular and Medical Virology at Ruhr University ...
Feb 9, 2023
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Investigators have identified new genetic variations effecting gene expression in the liver cells of patients of African ancestry, findings that provide insight into how drugs are metabolized differently in different populations, ...
Feb 8, 2023
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