Scientists have used 3-D models to break down the DNA behavior of cancer cells, in a breakthrough new study which could revolutionize treatment for the disease.
May 11, 2020
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A team of scientists led by the University of Michigan Rogel Cancer Center and Case Comprehensive Cancer Center has identified the binding site where drug compounds could activate a key braking mechanism against the runaway ...
Apr 20, 2020
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Pancreatic ductal adenocarcinoma (PDAC) cells maintain a high level of autophagy or degradation, allowing them to thrive in severely limiting microenvironments. However, the process via which autophagy promotes pancreatic ...
Medical investigators are theorizing that a combination of two treatments that activate myeloid cells may effectively treat a recalcitrant form of pancreatic cancer that thwarts conventional immunotherapy.
Cancer is not invincible but its weaknesses can be difficult to detect. An effort known as Project Achilles — named after the Greek warrior whose one vulnerability led to his undoing — was launched to develop a ...
Jul 11, 2011
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For the first time, scientists have confirmed the long-standing hypothesis that as people age, they accumulate gene mutations in their mitochondria—cells' energy source.
Apr 14, 2016
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Tumor cells typically alter their energy metabolism and increase glucose uptake to support their rapid division and spread. This limits glucose availability for immune cells and therefore dampens the body's anti-cancer immune ...
Feb 14, 2023
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Researchers at Inserm and Paris Descartes University have just taken an important step in research on stem cells and dental repair. They have managed to isolate dental stem cell lines and to describe the natural mechanism ...
Apr 22, 2015
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MIT cancer biologists have identified a new therapeutic target for small cell lung cancer, an especially aggressive form of lung cancer with limited options for treatment.
Nov 7, 2019
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A team led by University of Arizona researchers is taking a new, patient-directed approach to treating pancreatic cancer. Rather than relying on conventional cell lines that have defined effective drug targets for other types ...
Aug 4, 2016
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