New research on how cancer mutations influence a certain type of receptor on the cell membrane opens the way for the development of tailored drugs for certain cancers, such as rectal cancer and lung cancer. This, according ...
Feb 11, 2019
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SORLA is a protein trafficking receptor that has been mainly studied in neurons, but it also plays a role in cancer cells. Professor Johanna Ivaska's research group at Turku Bioscience observed that SORLA functionally contributes ...
Jan 29, 2021
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A hallmark of cancer is uncontrolled and sustained cell division. One particular overactive protein is implicated in this malfunction. EPFL scientists have discovered a complex mechanism that regulates this protein's activity ...
Aug 14, 2013
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Kinesins are motor proteins that "walk" along microtubules and transport various cargoes throughout the cell. A study in The Journal of Cell Biology uncovers an unexpected role for one kinesin in the pathway that regulates ...
Jan 27, 2014
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An international team led by scientists at The Scripps Research Institute (TSRI) has determined and analyzed the three-dimensional atomic structure of the human glucagon receptor. The receptor, found mainly on liver and kidney ...
Jul 17, 2013
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National Institutes of Health researchers used the popular anti-wrinkle agent Botox to discover a new and important role for a group of molecules that nerve cells use to quickly send messages. This novel role for the molecules, ...
May 2, 2013
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A properly functioning immune system is a lesson in balance, providing protection against disease without attacking healthy tissue. Work led by St. Jude Children's Research Hospital scientists and published recently in Nature ...
Apr 30, 2013
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Researchers at the University of California, San Diego School of Medicine have discovered a genetic risk factor for premature birth. The risk factor is related to a gene that codes for a protein that the scientists have found ...
May 6, 2014
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Making tiny changes to existing diabetes treatments can alter how they interact with cells, and potentially make the medicines more effective.
Apr 23, 2018
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When venom from animals such as spiders, snakes or cone snails is injected via a bite or harpoon, the cocktail of toxins delivered to its victim tends to cause serious reactions that, if untreated, can be lethal. But even ...
Feb 29, 2016
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