NAD+ (nicotinamide adenine dinucleotide), a key metabolite central to an efficient and healthy metabolism, declines with age. This previously unexplained phenomena is associated with numerous age-related diseases and has ...
Nov 16, 2020
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When antibody-producing immune cells encounter infectious pathogens for the first time, they engage a signal cascade to generate a massive activation signal within seconds. The mechanisms underlying this acute initial activation ...
Nov 5, 2020
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The immune response to infections is a delicate balance. We need just enough action to clear away the offending bacteria or viruses, but not so much that our own bodies suffer collateral damage.
Oct 15, 2020
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211
For most people, there is no scarier diagnosis than that of cancer. While treatments including chemotherapy and radiotherapy have been used since the 1940s and late 1800s, respectively, immunotherapy has more recently emerged ...
Sep 21, 2020
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56
For more than a decade, scientists have accepted that cholesterol—a key component of cell membranes—did not uniformly affect membranes of different types. But a new study led by Assistant Professor Rana Ashkar of the ...
Sep 8, 2020
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43
Pregnant mice fed a diet high in omega-6 fats and low in omega-3 fats produce offspring that go on to exhibit "hedonic"—pleasurable but excessive—levels of consumption of hyper-caloric diets, according to researchers ...
Sep 4, 2020
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59
All cancers are the result of cells that have gone haywire, multiplying out of control and expanding beyond their normal constraints. But not all tumors are the same: for reasons that remain poorly understood, some are more ...
Sep 3, 2020
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54
A new study from Washington University School of Medicine in St. Louis identifies a specific gene's previously unknown role in fertility. When the gene is missing in fruit flies, roundworms, zebrafish and mice, the animals ...
Aug 31, 2020
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65
Scientists at the University Bath have discovered a series of protein structures that are thought to be highly relevant to the onset of Parkinson's disease. It is hoped that further analysis of these structures will open ...
Aug 20, 2020
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248
More than 600,000 people worldwide have fallen victim to the lung disease COVID-19 so far, which is caused by the SARS coronavirus-2 (SARS-CoV-2). In order to obtain an effective therapy for COVID-19 as quickly as possible, ...
Jul 22, 2020
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