Diseases, Conditions, Syndromes

A sulfur molecule to block the coronavirus

The cell membrane is impermeable to viruses—to get inside and infect a cell, they use a range of strategies to exploit the cellular and biochemical properties of the membranes. The thiol-mediated uptake of organic molecules ...

Medical research

Chronic inflammation causes a reduction in NAD+

NAD+ (nicotinamide adenine dinucleotide), a key metabolite central to an efficient and healthy metabolism, declines with age. This previously unexplained phenomena is associated with numerous age-related diseases and has ...

Immunology

Researchers uncover new mechanism of immune-cell activation

When antibody-producing immune cells encounter infectious pathogens for the first time, they engage a signal cascade to generate a massive activation signal within seconds. The mechanisms underlying this acute initial activation ...

Medical research

Cholesterol's effects on cellular membranes

For more than a decade, scientists have accepted that cholesterol—a key component of cell membranes—did not uniformly affect membranes of different types. But a new study led by Assistant Professor Rana Ashkar of the ...

Medical research

How mechanical forces nudge tumors toward malignancy

All cancers are the result of cells that have gone haywire, multiplying out of control and expanding beyond their normal constraints. But not all tumors are the same: for reasons that remain poorly understood, some are more ...

Genetics

Genetic mutations may be linked to infertility, early menopause

A new study from Washington University School of Medicine in St. Louis identifies a specific gene's previously unknown role in fertility. When the gene is missing in fruit flies, roundworms, zebrafish and mice, the animals ...

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