A study by scientists of the German Center for Neurodegenerative Diseases (DZNE) points to a potential approach against Alzheimer's disease. In studies with mice, the researchers were able to show that blocking a particular ...
May 4, 2018
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Helicobacter pylori, the leading cause of peptic ulcer disease and stomach cancer. One factor important to H. pylori infection is the pore-forming toxin VacA. It is thought to gain entry into host cells by binding to specialized ...
Apr 24, 2018
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Every year, more than 100 million people worldwide develop the sexually transmitted disease gonorrhoea, with health consequences such as infertility, transmission of the disease to newborn babies, and increased risk of HIV ...
Mar 30, 2018
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For years, researchers have attempted to harness the full potential of gene therapy, a technique that inserts genes into a patient's cells to treat aggressive diseases such as cancer. But getting engineered DNA molecules ...
Feb 27, 2018
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Protein systems, such as Ras, make up the complex signaling pathways that control whether a cell divides or, in some cases, becomes cancerous and metastasizes into other regions of the body. For example, 98 percent of pancreatic ...
Feb 18, 2018
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In a new study, researchers from the universities of Uppsala and Lund show why insulin secretion is not working properly in patients suffering from type-2 diabetes. The report is published in the journal Cell Metabolism.
Feb 6, 2018
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The drug Gefitinib is used to treat breast, lung, and other cancers by inhibiting epidermal growth factor receptor (EGFR) signaling, but it has only a limited effect on prostate cancer. EGFR, present on the cell membrane, ...
Dec 22, 2017
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Researchers at Charité's NeuroCure Cluster of Excellence have successfully identified the mechanism behind rapid signal transmission. Their work, published in the current issue of Nature Neuroscience, shows that bridging ...
Dec 14, 2017
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You are what you eat when it comes to fat, report scientists from McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth) in the journal Science Advances.
Dec 1, 2017
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Sphingolipids – long-chain fatty acid molecules found in cell membranes – are broken down by sphingomyelinase enzymes into bioactive products such as ceramide. Growing evidence suggests roles for sphingolipid metabolites ...
Nov 2, 2017
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