SORLA is a protein that influences the balance of metabolic processes in adipose tissue, a particular form of fat. Too much of it makes fat cells overly sensitive to insulin, which leads them to break down less fat. SORLA ...
Jun 21, 2016
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From tracking activities within bacteria to creating images of molecules that make up human hair, several experiments have already demonstrated the unique abilities of the revolutionary imaging technique called multi-isotope ...
Jan 15, 2012
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The development of the brain requires an elaborate, tightly organized chain of events that are jumpstarted by neural stem cells, which give rise to increasingly specialized cells that carry out all brain functions. But what ...
Oct 26, 2023
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Inflammation and cell stress play important roles in the death of insulin-secreting cells and are major factors in diabetes. Cell stress also plays a role in Wolfram syndrome, a rare, genetic disorder that afflicts children ...
Aug 7, 2012
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Myc is a cancer-causing gene responsible for disrupting the normal 24-hour internal rhythm and metabolic pathways in cancer cells, found a team led by researchers from the Perelman School of Medicine at the University of ...
Sep 17, 2015
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A new spectroscopic technique reveals that glucose use in live cells provides valuable information about the functional status of cells, tissues, and organs. Shifts in a cell's use of glucose can signal changes in health ...
Jul 23, 2019
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247
Researchers at the University of Pittsburgh School of Medicine are the first to grow genetically modified miniature human livers in the laboratory, to emulate human liver disease progression and test therapeutics.
Aug 6, 2019
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Researchers have discovered a previously unknown way that pancreatic cells decide how much insulin to secrete. It could provide a promising new target to develop drugs for boosting insulin production in people with Type 2 ...
Nov 13, 2020
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Dynamic networks that specialize in the transmission of information generally consist of multiple components, including not only primary processors, like computers, for example, but also numerous support applications and ...
Sep 16, 2020
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Understanding why we overeat unhealthy foods has been a long-standing mystery. While we know food's strong power influences our choices, the precise circuitry in our brains behind this is unclear. The vagus nerve sends internal ...
Jan 18, 2024
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