Combining a new class of drug with two other compounds can significantly shrink lung tumours in mice and human cancer cells, finds a new study led by the Francis Crick Institute and The Institute of Cancer Research, London.
Sep 18, 2019
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A woman's bone marrow may determine her ability to start and sustain a pregnancy, report Yale researchers in PLOS Biology. The study shows that when an egg is fertilized, stem cells leave the bone marrow and travel via the ...
Sep 12, 2019
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The ARID1A tumor suppressor protein is required to maintain telomere cohesion and correct chromosome segregation after DNA replication. This finding, reported by Wistar researchers in Nature Communications, indicates that ...
Sep 6, 2019
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Much of the research on the underlying causes of Alzheimer's disease focuses on amyloid beta (Aß), a protein that accumulates in the brain as the disease progresses. Excess Aß proteins form clumps or "plaques" that disrupt ...
Aug 30, 2019
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UT Health San Antonio researchers have discovered a novel way to kill cancers that are caused by an inherited mutation in BRCA1, the type of cancer for which actress Angelina Jolie had preventive double mastectomy and reconstructive ...
Aug 27, 2019
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Cancer deploys a vast array of resources to grow: from instability in its genome to inflammation, as well as the creation of new blood vessels, the microenvironment surrounding the tumour, and the use of mechanisms that allow ...
Aug 21, 2019
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Researchers believe that stuttering—a potentially lifelong and debilitating speech disorder—stems from problems with the circuits in the brain that control speech, but precisely how and where these problems occur is unknown. ...
Aug 19, 2019
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In 2006, scientists discovered a way to "reprogram" mature cells—adult skin cells, for example—into stem cells that could, in principle, give rise to any tissue or organ in the body. Many assumed it was only a matter ...
Aug 19, 2019
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Two known gene mutations induce pathways that enhance pancreatic cancer's ability to invade tissues and evade the immune system. Researchers report the molecular details of this process, providing insights into druggable ...
Aug 5, 2019
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Neurodevelopmental disorders arising from rare genetic mutations can cause atypical cognitive function, intellectual disability, and developmental delays, yet it is unclear why and how this happens. Scientists suspected a ...
Jul 30, 2019
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