Nonsense-mediated RNA decay, or NMD, is an evolutionarily conserved molecular mechanism in which potentially defective messenger RNAs, or mRNAs, are degraded. By reducing errors in gene expression, it serves as an RNA quality ...
Feb 3, 2022
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Herpes simplex virus (HSV) is extremely common, affecting nearly two-thirds of the world's population, according to the World Health Organization.
Dec 14, 2023
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Some genes are known to drive cancer, and astonishing new research shows why: Mutations in the noncoding regions become functional, altering the abundance of messenger RNA, or mRNA, and potentially facilitating cell proliferation. ...
Apr 18, 2024
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More powerful gene-sequencing tools have increasingly been uncovering disease secrets in DNA within the cell nucleus. Now a research team is expanding those rapid next-generation sequencing tests to analyze a separate source ...
Jan 29, 2013
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In a paper published today in Diabetologia, a team at Joslin Diabetes Center, headed by Mary R. Loeken, PhD, has identified the enzyme AMP kinase (AMPK) as key to the molecular mechanism that significantly increases the risk ...
Oct 17, 2011
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Many people have felt the sudden and uncontrollable urge to eat a certain food. These urges—known as cravings—are very common, mostly during pregnancy. At this stage, the mother's body undergoes a series of physiological ...
Apr 4, 2022
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Many people have experienced the struggles of dealing with low back pain. A common cause of this pain is degeneration of intervertebral disks (IVDs), which are located between the vertebrae and help give the spinal column ...
Apr 18, 2022
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A study in The Journal of Cell Biology shows how a transcription factor called STAT3 remains in the axon of nerve cells to help prevent neurodegeneration. The findings could pave the way for future drug therapies to slow ...
Oct 29, 2012
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The same mechanism that stabilises the DNA in the cell nucleus is also important for the structure and function of vertebrate muscle cells. This has been established by RUB-researchers led by Prof. Dr. Wolfgang Linke (Institute ...
Jan 23, 2012
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It has been almost 20 years since the human genome was first sequenced, but researchers still know little about how the genome is folded up and organized within cells. In a paper to be published August 28 in the Journal of ...
Aug 28, 2018
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