Immunology

Antibodies gather and form a circle for defensive attack

Antibodies play a crucial role in our immune system by linking antigen recognition with complement activation for attacking foreign cells. Using high-speed atomic force microscopy, collaborative groups, including researchers ...

Neuroscience

Why nerve cells in the brain process information differently

The dentate gyrus is the "input point" for the hippocampus part of the brain. It transmits information from the short term memory to the long term. It consists of granule cells, which are especially dense in this area of ...

Neuroscience

Molecular bodyguards against Parkinson's disease

Chaperone proteins in human cells dynamically interact with the protein α-Synuclein, which is strongly associated with Parkinson's disease. A disturbed relationship to these "bodyguards" leads to cell damage and the formation ...

Gerontology & Geriatrics

Why ageing should be classified as a disease

Since the time of the ancient Greeks, doctors and philosophers have argued whether ageing is a disease or a natural process. Many authors of the Hippocratic Corpus argued that growing old invariably leads to frailty, disability ...

Diseases, Conditions, Syndromes

FDA-approved drug shows promise against ALS in mice

The cause of amyotrophic lateral sclerosis (ALS)—a disabling neurodegenerative disease that affects nerve cells in the brain and spinal cord and leads to weakened muscles and early death—is not fully understood, but accumulating ...

Medical research

Rapamycin may slow skin aging, study reports

The search for youthfulness typically turns to lotions, supplements, serums and diets, but there may soon be a new option joining the fray. Rapamycin, a FDA-approved drug normally used to prevent organ rejection after transplant ...

Neuroscience

How Alzheimer's disease spreads through the brain

Tau can quickly spread between neurons but is not immediately harmful, according to research in mouse neurons published in JNeurosci. Intervening during the initial accumulation of tau could potentially halt the progression ...

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