Scientists at A*STAR's Institute of Molecular and Cell Biology (IMCB) have made a landmark discovery in the battle against the rapid spread of aggressive cancers associated with PRL-3 oncoprotein . Contrary to the current ...
Sep 8, 2011
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Malignant melanoma, a dangerous type of skin cancer, deploys an elegant molecular mechanism to evade natural immune responses and the therapies intended to boost them, according to new work led by scientists at the Herbert ...
Jul 31, 2023
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Vanderbilt researchers have identified a protein that is key to the "education" of immature T cells in the thymus. The findings, reported in the Journal of Experimental Medicine, could inform therapeutic strategies for enhancing ...
Sep 2, 2022
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It may soon be possible to test a person for cancer with just a drop of their blood and a small machine. As part of a European research project, scientists have developed a device for detecting the HSP70 protein, which is ...
Nov 2, 2012
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Around 1% of patients with HIV - known as elite controllers - are able to survive without antiviral treatment, because their immune systems produce certain kinds of HIV-specific antibodies: proteins that recognise features ...
May 25, 2017
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Cells making slippery mucus provide a sticking point for disease-causing bacteria in the gut, according to a study published on October 3 in the Journal of Experimental Medicine.
Oct 3, 2011
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Researchers have long known that dozens of inherited diseases, called toxic proteinopathies, are caused by the build-up of specific misfolded proteins in cells. But, the molecular mechanisms responsible for this accumulation ...
Jul 25, 2019
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Metastasizing cancer cells often express integrins that provide better traction. A new study in The Journal of Cell Biology reveals how a lipid-converting enzyme helps the cells mobilize these integrins.
Jan 23, 2012
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During fetal development of the mammalian brain, the cerebral cortex undergoes a marked expansion in surface area in some species, which is accommodated by folding of the tissue in species with most expanded neuron numbers ...
Apr 26, 2013
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Protein systems, such as Ras, make up the complex signaling pathways that control whether a cell divides or, in some cases, becomes cancerous and metastasizes into other regions of the body. For example, 98 percent of pancreatic ...
Feb 18, 2018
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