By silencing the molecular pathway that prevents macrophages from attacking our own cells, University of Pennsylvania engineers have manipulated these white blood cells to eliminate solid tumors.
Jun 12, 2023
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574
Even though the COVID-19 public health emergency classification will expire this spring, the lingering effects of the pandemic remain. A constant puzzle to solve since the first year of the pandemic has been "long COVID," ...
Feb 14, 2023
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138
Metformin, the most prescribed drug for treating diabetes mellitus, known as type 2 diabetes, requires the presence of the growth differentiation factor 15 (GDF15)—a protein whose expression increases in response to cellular ...
Dec 16, 2022
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24
Roughly one in five cancer patients benefit from immunotherapy—a treatment that harnesses the immune system to fight cancer. Such an approach to beating cancer has seen significant success in lung cancer and melanoma, among ...
May 17, 2024
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81
It was previously assumed that bones lacked lymphatic vessels, but new research from the MRC Human Immunology Unit at Oxford's MRC Weatherall Institute for Molecular Medicine not only locates them within bone tissue, but ...
Jan 20, 2023
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124
Engineered immune cells, known as CAR T cells, have shown the world what personalized immunotherapies can do to fight blood cancers. Now, investigators have reported highly promising early results for CAR T therapy in a small ...
Nov 23, 2022
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913
When a hunting dog picks up the scent of a deer, it sometimes freezes. On the spot. The same thing can happen to people who need to concentrate on a challenging task.
Jul 29, 2023
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131
As we age, the end caps of our chromosomes, called telomeres, gradually shorten. Now, Salk scientists have discovered that when telomeres become very short, they communicate with mitochondria, the cell's powerhouses. This ...
Feb 8, 2023
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323
Eating too much salt, which is common in many Western societies, is not only bad for our blood pressure and cardiovascular system—it could also adversely impact the immune system.
Feb 9, 2023
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398
For the first time in the world: a team of researchers from Tel Aviv University and the Israel Institute for Biological Research have developed an mRNA-based vaccine that is 100% effective against a type of bacteria that ...
Mar 9, 2023
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190
