Genetics

Diabetic fruit flies support buzz about dietary sugar dangers

Regularly consuming sucrose—the type of sugar found in many sweetened beverages—increases a person's risk of heart disease. In a study published January 10 in the journal PLOS Genetics, researchers at Sanford-Burnham ...

Medical research

Study discovers that stem cell senescence drives aging

Declining levels of the protein BubR1 occur when both people and animals age, and contribute to cell senescence or deterioration, weight loss, muscle wasting and cataracts. Mayo Clinic researchers have shown that adult progenitor ...

Oncology & Cancer

Scientists find Achilles' heel of cancer cells

Several substances inhibiting so-called HDAC enzymes have been studied in trials searching for new anti-cancer drugs in recent years. "Trials have shown that HDAC inhibitors are very effective in arresting growth of cultured ...

Oncology & Cancer

Genetic master controls expose cancers' Achilles' heel

In a surprising finding that helps explain fundamental behaviors of normal and diseased cells, Whitehead Institute scientists have discovered a set of powerful gene regulators dubbed "super-enhancers" that control cell state ...

Oncology & Cancer

Clues from DNA could predict growth of prostate cancer

Researchers from the UCLA Jonsson Comprehensive Cancer Center and other institutions in the U.S., Canada, the United Kingdom and Singapore, have identified 1,178 biomarkers in men's genomes—the complete set of genetic material ...

Genetics

Researchers discover new mechanism for human gene expression

In a study that could change the way scientists view the process of protein production in humans, University of Chicago researchers have found a single gene that encodes two separate proteins from the same sequence of messenger ...

Medical research

A new puzzle piece to control the aging and age-related diseases

A basic discovery of how the cellular functions are connected to control aging is presented in the journal Cell Metabolism. The study shows that an increasingly deteriorating communication between the cells' organelles is ...

Cardiology

Neonatal heart stem cells may help mend kids' broken hearts

Researchers at the University of Maryland School of Medicine, who are exploring novel ways to treat serious heart problems in children, have conducted the first direct comparison of the regenerative abilities of neonatal ...

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