For the first time, researchers have shown that an enzyme key to regulating gene expression—and also an oncogene when mutated—is critical for the expression of numerous inflammatory compounds that have been implicated ...
Feb 3, 2016
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23
A group of Kobe University researchers have revealed that adding Vitamin B2 to cells that have been exposed to aging stress increases the mitochondria's ability to produce energy and prevents cell aging. The research group ...
Dec 13, 2021
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67
A potentially effective treatment for diabetic retinopathy, a disease that swells and scars the retina, has been developed by an Université de Montréal scientist and investigator at Maisonneuve-Rosemont Hospital Research ...
Feb 11, 2021
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16
Thanks to advances in cancer therapies, most forms of breast cancer are highly treatable, especially when caught early.
Dec 15, 2022
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Buck Institute researchers have discovered and are developing a novel, non-invasive biomarker test that can be used to measure and track performance of senolytics: a class of drugs that selectively eliminate senescent cells. ...
Apr 2, 2021
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A new editorial paper, titled "The senescence-associated secretory phenotype induces neuroendocrine transdifferentiation," was recently published in the journal Aging
May 12, 2023
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3
Since the time of the ancient Greeks, doctors and philosophers have argued whether ageing is a disease or a natural process. Many authors of the Hippocratic Corpus argued that growing old invariably leads to frailty, disability ...
Nov 27, 2019
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35
Changes to the structure of the protein histone H3.3 may play a key role in silencing genes that regulate cancer cell growth, according to a study led by researchers from the Icahn School of Medicine at Mount Sinai and published ...
Nov 21, 2014
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0
After decades of fundamental scientific and drug discovery research, Alzheimer's disease has remained inscrutable and incurable, with a bare minimum of therapeutic progress. But in a new review article in Nature Neuroscience, ...
Jan 3, 2023
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82
Senescent cells—those that have lost the ability to divide—accumulate with age and are key drivers of age-related diseases, such as cancer, dementia and cardiovascular disease. In a new study, a team led by University ...
Jun 30, 2022
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