Oncology & Cancer

Mechanisms ID'd for curcumin resensitization of cancer cells

(HealthDay)—Curcumin can resensitize chemoresistant pancreatic ductal adenocarcinoma (PDAC) cells through inhibition of the polycomb repressive complex 2 (PRC2)-PVT1-c-Myc axis, according to a study published online July ...

Medical research

Researchers discover a new player in tumor suppression and aging

A study conducted by the Spanish National Cancer Research Centre´s (CNIO) Genomic Instability Group, led by Óscar Fernández-Capetillo, describes for the first time in mammals, the role played by the SMC5/6 protein complex ...

Oncology & Cancer

Research proposes new way to reverse resistance to chemotherapy

A serious medical problem that oncologists face is multi-drug resistant cancers. In order to address this issue, Guillermo Aquino-Jarquín from the Children's Hospital Federico Gómez of Mexico, seeks expression profiles ...

Medical research

3-D printing offers innovative method to deliver medication

3-D printing could become a powerful tool in customizing interventional radiology treatments to individual patient needs, with clinicians having the ability to construct devices to a specific size and shape. That's according ...

Oncology & Cancer

Increased toxicity for many newly approved anticancer drugs

(HealthDay)—Newly approved anticancer drugs that do not have a specific molecular target on cancer cells are associated with increased toxicity and the accompanying costs of management, according to research published online ...

Oncology & Cancer

AACR: tumor vulnerability varies with clonal evolution in ALL

(HealthDay)—In acute lymphoblastic leukemia (ALL), tumor vulnerability to different chemotherapeutic agents varies at different stages of clonal evolution, which could represent a viable strategy in avoiding drug resistance. ...

Oncology & Cancer

Tailoring treatment in ovarian cancer

(Medical Xpress)—The prognosis for ovarian cancer patients is poor with only 3 out of 10 women living at least 5 years after diagnosis. Clinicians urgently need the tools to provide a more accurate prognosis for patients ...

Oncology & Cancer

Neurotoxicity of chemotherapy drugs

Chemotherapy is one of the primary treatments for cancer. However, one of the most disturbing findings of recent studies of cancer survivors is the apparent prevalence of chemotherapy-associated adverse neurological effects, ...

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