Post-surgical radiotherapy and temozolomide, a chemotherapeutic drug, targeting post-cell division is the current standard of care for glioblastoma (GBM)—the most prevalent and lethal primary tumor of the central nervous ...
Jan 18, 2023
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Chromatin comprises a complex mixture of DNA and proteins that forms the structural basis of chromosomes in the cellular nuclei. When cells die, they release cell-free chromatin particles, or cfChPs, into the circulatory ...
Jan 16, 2023
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Researchers from the Suzhou Institute of Biomedical Engineering and Technology (SIBEBT) of the Chinese Academy of Sciences (CAS) have revealed the reasons for the inevitable occurrence of multidrug resistance during tumor ...
May 18, 2022
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In 1986, cellular biochemist Kazumitsu Ueda, currently at Kyoto University's Institute for Integrated Cell-Material Sciences (iCeMS), discovered that a protein called ABCB1 could transport multiple chemotherapeutics out of ...
Dec 29, 2020
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Researchers have found a way to help make chemotherapy more effective in treating colon cancer. They identified a new pathway (RICTOR/mTORC2) as a biological target for the disease. Targeted inhibition of RICTOR or the mTORC2 ...
Jan 13, 2020
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Tumor volume in a preclinical model of triple negative breast cancer (TNBC) was reduced four times more when an experimental polo-like kinase 1 (PLK1) inhibitor was combined with a standard-of-care chemotherapeutic agent ...
Dec 10, 2019
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A team of scientists from Skoltech Center for Energy Science and Technology, the Institute for Problems of Chemical Physics of Russian Academy of Sciences and National Taiwan University has discovered that fullerene compounds ...
Oct 21, 2019
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Researchers at the Bellvitge Biomedical Research Institute (IDIBELL), with the participation of collaborators from the Baylor College of Medicine (Houston) and the University Institute of Oncology of Asturias (IUOPA), publish ...
Jun 18, 2019
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AICAr (5-amino-4-imidazolecarboxamide riboside, also called Acadesine) has been found to inhibit cell proliferation and has cytotoxic potential for childhood acute lymphoblastic leukemia (ALL) cells. Much of the drug's cytotoxic ...
Jan 31, 2019
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Cancer treatments are suspected to accelerate certain aging processes in the body. A new study has found that indicators of such biological aging correlate with declines in cognitive function in women who had undergone breast ...
Nov 26, 2018
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