Mount Sinai researchers have identified a protein produced by the immune system—granulocyte-colony stimulating factor (G-CSF)—that could be responsible for the development of cocaine addiction.
Jan 16, 2018
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New research from Mount Sinai Medical Center in New York reveals that repeated exposure to cocaine decreases the activity of a protein necessary for normal functioning of the brain's reward system, thus enhancing the reward ...
Apr 22, 2012
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Researchers at the University of Cambridge have identified abnormal brain structures in the frontal lobe of cocaine users' brains which are linked to their compulsive cocaine-using behaviour. Their findings were published ...
Jun 21, 2011
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When glutamate and dopamine do not collaborate as they should in the brain's signal system, the kick that alcohol, sugar, or other drugs induce increases. This is shown in a new Swedish-Canadian study on mice being published ...
Aug 30, 2011
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Research published by Cell Press in the January 12 issue of the journal Neuron provides fascinating insight into a newly discovered brain mechanism that limits the rewarding impact of cocaine. The study describes protective ...
Jan 11, 2012
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Medicines which increase levels of the brain chemical dopamine may hold the key to helping those addicted to cocaine and amphetamines kick the habit, researchers from the University of Cambridge have found.
Oct 7, 2011
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It is often said that once people develop an addiction, they can never completely eliminate their attraction to the abused substance. New findings provide further support for this notion by suggesting that even long-term ...
Sep 23, 2013
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Researchers at The University of Texas at Arlington are studying how fluctuating estrogen levels make females increasingly sensitive to the rewarding effects of cocaine and ultimately, vulnerable to cocaine addiction.
Aug 3, 2016
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Chronic exposure to cocaine reduces the expression of a protein known to regulate brain plasticity, according to new, in vivo research on the molecular basis of cocaine addiction. That reduction drives structural changes ...
May 9, 2012
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It is well established that a mood disorder can increase an individual's risk for substance abuse, but there is also evidence that the converse is true; substance abuse can increase a person's vulnerability to stress-related ...
Aug 24, 2011
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