Nucleus accumbens in the brain play a central role in the risk-reward circuit. Their operation is based chiefly on three essential neurotransmitters: dopamine, which promotes desire; serotonin, whose effects include satiety ...
Oct 29, 2020
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Cocaine use produces structural changes in the brain reducing the volume of certain regions, and also functional changes affecting motivational and cognitive processes. These changes favour addiction. The objective of a project ...
Mar 5, 2014
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A heartbreaking phenomenon of addiction is that just a brief stressful episode can trigger relapse. In a detailed new cocaine addiction study conducted in rat models, which closely parallel human addictive behavior, scientists ...
Apr 11, 2017
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(Medical Xpress) -- Women who are clinically depressed at the time they enter drug court have a substantially higher risk of using crack cocaine within four months, according to a new study. Because current but not past depression ...
Jul 14, 2011
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(Medical Xpress)—A team of researchers affiliated with the University of Michigan and the University of Alabama has found two molecules expressed in rats that are involved in their response to cocaine and other stimulants. ...
Medicines which increase levels of the brain chemical dopamine may hold the key to helping those addicted to cocaine and amphetamines kick the habit, researchers from the University of Cambridge have found.
Oct 7, 2011
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Washington State University researchers have found a cellular mechanism that contributes to the lack of motivation and negative emotions of a cocaine addict going through withdrawal. Their discovery, published in the latest ...
Sep 10, 2012
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New research from the University of California, Irvine, finds that drug withdrawal-induced anxiety and reinstatement of drug seeking behaviors are controlled by a single pathway in the brain and centered around dopamine cells.
May 3, 2022
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An international team led by scientists at The Scripps Research Institute (TSRI) has found strong evidence supporting a new strategy against drug addiction. The researchers showed that a compound that inhibits the activity ...
Aug 18, 2016
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Since mephedrone was made illegal in the UK in 2010, the street price of the drug has risen while the quality has degraded, which in turn may have reduced use of the drug. New research published online today reveals that ...
Jan 18, 2012
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