Collagen type XII plays a key role in regulating the organization of the tumor matrix, reveals a new study from the Garvan Institute of Medical Research. A team of scientists led by Associate Professor Thomas Cox, Head of ...
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Implantable devices that release insulin into the body hold promise as an alternative way to treat diabetes without insulin injections or cannula insertions. However, one obstacle that has prevented their use so far is that ...
Aug 05, 2022
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A new clinical-grade collagen made from discarded bullfrog skin is leapfrogging from the lab bench to clinics soon.
Jul 27, 2022
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Cancer cells produce small amounts of their own form of collagen, creating a unique extracellular matrix that affects the tumor microbiome and protects against immune responses, according to a new study by researchers at ...
Jul 21, 2022
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In the presence of pancreatic tumors, certain immune cells break down structural proteins into molecules that trigger the building of dense tissue, a known barrier to therapy, a new study finds.
Apr 04, 2022
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Collagen is a building block that can be hierarchically assembled into diverse morphological structures that are dynamically adaptive in response to external cues. Materials scientists have limited capabilities of guiding ...
Myocardial infarction, or a heart attack, affects over 800,000 people in the U.S. every year. Following a heart attack, a scar forms on the heart, leading to poorer heart function, and ultimately, it could lead to heart failure. ...
Jan 19, 2022
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Mount Sinai researchers have solved a major mystery in cancer research: How cancer cells remain dormant for years after they leave a tumor and travel to other parts of the body, before awakening to create metastatic cancer.
Dec 13, 2021
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Back pain affects many people at some point in their lives, and a common cause is damage to the squishy discs or flexible, rubbery tissues of the spine. However, observing this damage at an early stage is difficult with current ...
Dec 08, 2021
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Muscle dystrophy describes a set of diseases that causes the weakening and loss of muscle. Ullrich congenital muscular dystrophy is a rare disease that is the result of a mutation in one or more three COL6 genes, resulting ...
Dec 02, 2021
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Collagen /ˈkɒlədʒɨn/ is a group of naturally occurring proteins found in animals, especially in the flesh and connective tissues of mammals. It is the main component of connective tissue, and is the most abundant protein in mammals, making up about 25% to 35% of the whole-body protein content. Collagen, in the form of elongated fibrils, is mostly found in fibrous tissues such as tendon, ligament and skin, and is also abundant in cornea, cartilage, bone, blood vessels, the gut, and intervertebral disc. The fibroblast is the most common cell which creates collagen.
In muscle tissue, it serves as a major component of the endomysium. Collagen constitutes one to two percent of muscle tissue, and accounts for 6% of the weight of strong, tendinous muscles. Gelatin, which is used in food and industry, is collagen that has been irreversibly hydrolyzed.
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