Diseases, Conditions, Syndromes

Researchers trace a form of lupus back to a single mutation

Sometimes a single mutation in our genetic make-up is enough to cause disease. This is also the case with the autoimmune disease lupus. Lupus causes severe inflammation throughout the body and can have a serious impact on ...

Diseases, Conditions, Syndromes

Possible trigger of chronic inflammatory bowel disease identified

As the cause of chronic inflammatory bowel diseases (IBD) such as Crohn's disease or ulcerative colitis is not yet known, treatment for sufferers is currently aimed at alleviating the often agonizing symptoms. The discovery ...

Oncology & Cancer

The role of p53 as a target for novel cancer therapies

The p53 tumor suppressor protein is encoded by TP53, the most frequently mutated gene in cancer. A review article published in Nature Reviews Clinical Oncology by Professor Klas G Wiman and colleagues at the Department of ...

Medical research

Bile duct function and disease highlighted in new study

Research from the Gupta Lab provides important insights into the extrahepatic bile ducts. These bile ducts outside of the liver are a critical but poorly understood component of the human digestive system. The study, led ...

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