Oncology & Cancer

New computer simulation cracks mystery of cancer drug resistance

Imatinib, better known as Gleevec, was hailed as a "miracle" cancer drug when it entered the market in the early 2000s. Though it has been highly successful at treating early-stage chronic myeloid leukemia (CML)—a rare ...

Oncology & Cancer

New target for treating wide spectrum of cancers

(Medical Xpress)—UC Irvine biologists, chemists and computer scientists have identified an elusive pocket on the surface of the p53 protein that can be targeted by cancer-fighting drugs. The finding heralds a new treatment ...

Medical research

Disease-causing tangle could spawn new materials

When most people hear the word amyloid, they immediately think of Alzheimer's disease. And indeed, it was in the brains of Alzheimer's patients that these dense protein masses were first identified. But it turns out that ...