In order to colonize other organs and grow into metastases, tumor cells that detach from the parent tumor need to manipulate their new microenvironment and create a 'metastatic niche.' Scientists from the German Cancer Research ...
Mar 23, 2020
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During the past ten years, scientists who study how the human body develops and functions on the most basic level have enjoyed a renaissance of sorts, thanks to structures called organoids—tiny 3D models of organs developed ...
Feb 16, 2022
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Scientists at the Gladstone Institutes and the University of California, San Francisco (UCSF), together with collaborators in Europe, discovered that a common type of cell within the human reproductive and intestinal tracts ...
Feb 16, 2017
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New knowledge on the cellular makeup and growth of teeth can expedite developments in the treatment of tooth sensitivity and regenerative dentistry—a biological therapy for damaged teeth. The study, which was conducted ...
Sep 23, 2020
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Scientists at the Gladstone Institutes have invented a new way to create three-dimensional human heart tissue from stem cells. The tissue can be used to model disease and test drugs, and it opens the door for a precision ...
Apr 20, 2016
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Stem cells from patients with a rare form of muscular dystrophy have been successfully transplanted into mice affected by the same form of dystrophy, according to a new study published today in Science Translational Medicine.
Jun 27, 2012
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Congenital diaphragmatic hernia (CDH) is not as well known as muscular dystrophy and cystic fibrosis, but like them it is a life-threatening birth defect, and is just as common. Occurring in one in 3,000 births, CDH causes ...
Mar 25, 2015
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A new study shows the existence of a connection between atherosclerotic plaques and the central nervous system. This previously unknown "circuit" involves three systemically acting tissues, the immune system, the nervous ...
Apr 27, 2022
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249
Researchers at the Kimmel Cancer Center at Jefferson have shed new light on the longstanding conundrum about what makes a tumor grow—and how to make it stop. Interestingly, cancer cells accelerate the aging of nearby ...
May 26, 2011
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Many types of cancer are caused by gene mutations in the signalling pathways that control cell growth, such as the hedgehog signalling pathway. A new study from the Karolinska Institutet, published in the journal Nature Communications, ...
Aug 8, 2016
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