In a new study, scientists report that they substantially curbed weight gain, improved metabolism, and improved the efficacy of insulin in mice by engineering them to express a specific human enzyme in their fat tissue. Although ...
Nov 14, 2011
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The enzyme arginase-2 plays a major role in kidney failure, and blocking the action of this enzyme might lead to protection against renal disease in diabetes, according to researchers.
Nov 5, 2011
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Adult stem cells from mice converted to antigen-specific T cells -- the immune cells that fight cancer tumor cells -- show promise in cancer immunotherapy and may lead to a simpler, more efficient way to use the body's immune ...
Sep 20, 2011
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It's not the fountain of youth, but a fast-emerging class of drugs could bring us closer to achieving the age-old quest for longer life, better health, and greater vitality.
Jun 23, 2021
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Changes to the gut microbiome interacted with the immune system to slow the growth of cancer in mice exposed to cigarette smoke, according to research that was selected for presentation at Digestive Disease Week (DDW) 2020. ...
Apr 30, 2020
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Maternal use of the antidepressant fluoxetine (Prozac) can alter the brain circuits in her offspring that control behaviors reminiscent of autism spectrum disorder, suggests a study in mice published in eNeuro. These results ...
Jul 2, 2018
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In the December featured basic science article in The Journal of Nuclear Medicine, Belgian researchers report on the first large-scale longitudinal imaging study to evaluate BACE1 inhibition with micro-PET in mouse models ...
Dec 6, 2017
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Pain sensitivity associated with alcohol withdrawal may activate the same brain region in both drinking and non-drinking mice, finds a study published in eNeuro.
Jul 24, 2017
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In a new research report published online in The FASEB Journal, scientists used mice to show that chicoric acid, a component of chicory, may help reduce memory impairment associated with Alzheimer's disease, and possibly ...
Jan 10, 2017
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Most cells can divide only a limited number of times and eventually undergo permanent cell cycle arrest, a state known as cellular senescence. Cellular senescence is mediated by activation of specific cellular signaling pathways ...
Aug 4, 2016
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