New research by scientists at the University of Pittsburgh provides an unprecedented level of resolution and insight into disturbances in cortical GABAergic microcircuits, which are thought to underlie cognitive impairments ...
Jun 20, 2017
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Transcription factor Heat Shock Factor 1 (Hsf1), which the developing brain releases to shield the vital organ from the ravages of environmental stress, actually can contribute to impairing the embryonic brain when too much ...
May 2, 2017
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Researchers from King's College London have discovered that neuronal activity can stimulate tau release from healthy neurons in the absence of cell death. The results published by Diane Hanger and her colleagues in EMBO reports ...
Feb 15, 2013
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Researchers at the ULB – IRIBHM and ULB Neuroscience Institute – have tested the therapeutic potential of cortical neurons generated at the laboratory, by transplantation in the brains of adult mice. Their research is ...
Mar 6, 2015
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University of Iowa biologists have advanced the knowledge of human neurodevelopmental disorders by finding that a lack of a particular group of cell adhesion molecules in the cerebral cortex -- the outermost layer of the ...
Apr 30, 2012
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Many people who survive a heart attack find themselves back in the hospital with a failing heart just years later. And the outcome often is unfavorable, owing to limited treatment options. But scientists at Temple University ...
Sep 4, 2013
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An international research team led by The University of Tokyo modeled the growth of cerebral tracts. Using neurons derived from stem cells, they grew cortical-like spheroids. In a microdevice, the spheroids extended bundles ...
Apr 19, 2019
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Researchers at Emory University School of Medicine have gained insight into a feature of fragile X syndrome, which is also seen in other neurological and neurodevelopmental disorders.
Feb 8, 2019
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Neuroscientists at The Scripps Research Institute (TSRI) have filled in a significant gap in the scientific understanding of how neurons mature, pointing to a better understanding of some developmental brain disorders.
Jun 20, 2013
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Northwestern University-led researchers have created the first highly mature neurons from human induced pluripotent stem cells (iPSCs), a feat that opens new opportunities for medical research and potential transplantation ...
Jan 12, 2023
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